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The landscape of pharmaceutical treatments is constantly evolving, often spurred by new data from ongoing research and postmarketing surveillance. In the case of obeticholic acid (Ocaliva), prescribed for primary biliary cholangitis (PBC), recent FDA communications have raised critical safety flags. While its initial approval heralded hope for patients with this debilitating liver disease, subsequent findings
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On Thursday, the Consumer Financial Protection Bureau (CFPB) unveiled a landmark regulation aimed at curbing the rampant overdraft fees charged by banks. This initiative promises to significantly lessen the burden on American consumers, potentially saving them an astonishing $5 billion each year. The new guidelines allow banks to either charge a nominal fee of $5
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Jared Leto, the acclaimed actor and musician, is reportedly on the verge of finalizing a deal to join the illustrious cast of the forthcoming film *Assassination*, directed by Barry Levinson. This highly anticipated project, co-scripted by renowned playwright David Mamet, delves into the intricate conspiracy surrounding the assassination of President John F. Kennedy. Although the
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In recent days, a fierce wildfire, known as the Franklin fire, has engulfed parts of Malibu, California, prompting mass evacuations including local residents and high-profile celebrities. As powerful winds and steep canyons facilitated the spread of flames, firefighters were left scrambling to protect homes in one of the state’s most affluent areas. Initial reports indicate
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The automotive industry is poised for notable shifts as it approaches 2025, with U.S. car dealers experiencing a renewed sense of positivity that could shape their business strategies in the near future. Insights from Cox Automotive reveal that the optimism largely stems from the recent U.S. presidential election and prospective economic conditions, despite persistent uncertainties
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Chronic lymphocytic leukemia (CLL) presents significant therapeutic challenges, particularly in patients who have previously received treatments with conventional covalent Bruton’s tyrosine kinase (BTK) inhibitors. Recent clinical data from a Phase III study has shed light on the potential of pirtobrutinib, an innovative oral non-covalent BTK inhibitor, to improve outcomes for this group of patients. Presented
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